Extraction of Cuminum cyminum and Foeniculum vulgare Essential Oils and Their Antibacterial and Antibiofilm Activity against Clinically Isolated Porphyromonas gingivalis and Prevotella intermedia: An In Vitro Study

This study aimed to investigate the antibacterial and antibiofilm activities of essential oils Cuminum cyminum (CEO) Foeniculum vulgare (FEO) on clinically isolated Porphyromonas gingivalis (P. gingivalis) Prevotella intermedia intermedia). Subgingival plaque samples were collected from periodontal pockets (≥6 mm) patients with generalized severe periodontitis. Microbiological molecular tests performed isolate confirm P. intermedia. A previously was used. The hydrodistillation method used extract CEO FEO. activity examined against confirmed clinical strains determined using disc diffusion broth dilution methods determine minimum inhibitory (MIC) bactericidal concentrations (MBC). properties FEO tube method. t-test for comparisons inhibition zones. Both presented zones both bacteria. revealed MIC values 3.125 µL/mL MBC 6.25 gingivalis, respectively. In addition, their 0.195 µL/mL, Finally, showed moderate strong intermedia, supports Further studies should focus these as an adjunct therapy.